GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1359360
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mef2a
Name: myocyte enhancer factor 2a
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:13221266480464CTDTetrachlorodibenzodioxin results in increased expression of MEF2A mRNA

PMID:20106945, PMID:21632981, PMID:30096437
increases expressionISORGD:16216086480464CTDTetrachlorodibenzodioxin results in increased expression of MEF2A mRNA

PMID:24058054
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.