GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | HSPA1A | increases expression | EXP | | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of HSPA1A mRNA | PMID:20106945 | HSPA1A | multiple interactions | EXP | | 6480464 | CTD | [Tetrachlorodibenzodioxin co-treated with 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide] results in decreased expression of HSPA1A mRNA | PMID:29704546 | HSPA1A | affects expression | ISO | Hspa1a (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin affects the expression of HSPA1A mRNA | PMID:21570461 | HSPA1A | increases expression | ISO | Hspa1a (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of HSPA1A mRNA | PMID:17035482 | HSPA1A | increases expression | ISO | Hspa1a (Rattus norvegicus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of HSPA1A mRNA | PMID:33387578 | HSPA1A | multiple interactions | ISO | Hspa1a (Mus musculus) | 6480464 | CTD | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HSPA1A mRNA; Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to HSPA1A promoter] | PMID:17942748 PMID:19654925 | |
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