Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1348586
Species: Homo sapiens
RGD Object: Gene
Symbol: MAN2B1
Name: mannosidase alpha class 2B member 1
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects expressionISORGD:15510526480464CTDTetrachlorodibenzodioxin affects the expression of MAN2B1 mRNA

PMID:21570461
multiple interactionsISORGD:15510526480464CTD[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of MAN2B1 mRNA

PMID:16214954
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.