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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1348501
Species: Homo sapiens
RGD Object: Gene
Symbol: AP1S2
Name: adaptor related protein complex 1 subunit sigma 2
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
AP1S2decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of AP1S2 mRNAPMID:17101203
AP1S2increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of AP1S2 mRNAPMID:11489354
AP1S2affects expressionISOAp1s2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of AP1S2 mRNAPMID:21570461
AP1S2decreases expressionISOAp1s2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of AP1S2 mRNAPMID:19933214
AP1S2decreases expressionISOAp1s2 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of AP1S2 mRNAPMID:32109520 PMID:34747641
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