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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1348483
Species: Homo sapiens
RGD Object: Gene
Symbol: OSBPL8
Name: oxysterol binding protein like 8
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
OSBPL8affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of OSBPL8 mRNAPMID:22574217
OSBPL8affects expressionISOOsbpl8 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of OSBPL8 mRNAPMID:21570461
OSBPL8decreases expressionISOOsbpl8 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of OSBPL8 mRNAPMID:32109520 PMID:33387578
OSBPL8increases expressionISOOsbpl8 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of OSBPL8 mRNAPMID:20819909
OSBPL8multiple interactionsISOOsbpl8 (Mus musculus)6480464CTDTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to OSBPL8 gene]PMID:20819909
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