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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1347423
Species: Homo sapiens
RGD Object: Gene
Symbol: HLA-G
Name: major histocompatibility complex, class I, G
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HLA-Gaffects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of HLA-G mRNAPMID:22574217
HLA-Gincreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of HLA-G mRNAPMID:19619570
HLA-Gmultiple interactionsEXP 6480464CTD[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of HLA-G mRNAPMID:19619570
HLA-Gaffects expressionISOH2-M3 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of H2-M3 mRNAPMID:21570461
HLA-Gdecreases expressionISORT1-M3-1 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of RT1-M3-1 mRNAPMID:33387578 PMID:34747641
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