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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1345506
Species: Homo sapiens
RGD Object: Gene
Symbol: PDLIM2
Name: PDZ and LIM domain 2
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PDLIM2affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of PDLIM2 mRNAPMID:22298810
PDLIM2increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of PDLIM2 mRNAPMID:21632981 PMID:26238291
PDLIM2affects expressionISOPdlim2 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of PDLIM2 mRNAPMID:22298810
PDLIM2affects expressionISOPdlim2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of PDLIM2 mRNAPMID:21570461
PDLIM2decreases expressionISOPdlim2 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of PDLIM2 mRNAPMID:21215274 PMID:34747641
PDLIM2decreases expressionISOPdlim2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of PDLIM2 mRNAPMID:19770486
PDLIM2increases expressionISOPdlim2 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of PDLIM2 mRNAPMID:33387578
PDLIM2multiple interactionsISOPdlim2 (Rattus norvegicus)6480464CTDAHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of PDLIM2 mRNA]PMID:21215274
PDLIM2multiple interactionsISOPdlim2 (Mus musculus)6480464CTDKL protein inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of PDLIM2 protein]]; Tetrachlorodibenzodioxin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of PDLIM2 protein]PMID:29885354
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