GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CYP51A1 | decreases expression | ISO | Cyp51 (Rattus norvegicus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in decreased expression of CYP51 mRNA | PMID:21215274 PMID:32109520 PMID:34747641 | CYP51A1 | decreases expression | ISO | Cyp51 (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in decreased expression of CYP51 mRNA | PMID:28213091 PMID:28238261 PMID:28922406 | CYP51A1 | increases expression | ISO | Cyp51 (Rattus norvegicus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of CYP51 mRNA | PMID:26232522 PMID:33387578 | CYP51A1 | multiple interactions | ISO | Cyp51 (Mus musculus) | 6480464 | CTD | [Dietary Sucrose co-treated with Dietary Fats co-treated with bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in decreased expression of CYP51 mRNA; [Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of CYP51 mRNA; Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP51 gene] | PMID:28213091 PMID:28433925 PMID:30722647 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |