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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1344832
Species: Homo sapiens
RGD Object: Gene
Symbol: TNFSF10
Name: TNF superfamily member 10
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TNFSF10affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of TNFSF10 mRNAPMID:22298810
TNFSF10decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of TNFSF10 mRNAPMID:11007951 PMID:11489354
TNFSF10increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of TNFSF10 mRNAPMID:19619570
TNFSF10multiple interactionsEXP 6480464CTD[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of TNFSF10 mRNA; Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of TNFSF10 mRNA]PMID:11007951 PMID:19619570
TNFSF10affects expressionISOTnfsf10 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of TNFSF10 mRNAPMID:34747641
TNFSF10decreases expressionISOTnfsf10 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of TNFSF10 mRNAPMID:19520675 PMID:32109520
TNFSF10increases expressionISOTnfsf10 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of TNFSF10 mRNAPMID:12167310 PMID:14718643 PMID:15310856 PMID:21095216
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