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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1332483
Species: Mus musculus
RGD Object: Gene
Symbol: Slc4a4
Name: solute carrier family 4 (anion exchanger), member 4
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc4a4decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of SLC4A4 mRNAPMID:26290441
Slc4a4multiple interactionsEXP 6480464CTDTetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of SLC4A4 mRNA]PMID:16054899
Slc4a4affects expressionISOSlc4a4 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of SLC4A4 mRNAPMID:32109520
Slc4a4decreases expressionISOSlc4a4 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of SLC4A4 mRNAPMID:33387578
Slc4a4increases expressionISOSlc4a4 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of SLC4A4 mRNAPMID:16054898 PMID:18796159 PMID:21215274 PMID:22342509
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