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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1322795
Species: Mus musculus
RGD Object: Gene
Symbol: Crlf1
Name: cytokine receptor-like factor 1
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Crlf1decreases expressionISOCRLF1 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of CRLF1 mRNAPMID:20106945 PMID:21632981
Crlf1increases expressionISOCrlf1 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of CRLF1 mRNAPMID:32109520
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