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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1321879
Species: Mus musculus
RGD Object: Gene
Symbol: Rpp30
Name: ribonuclease P/MRP 30 subunit
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of RPP30 mRNA

PMID:21570461
multiple interactionsEXP 6480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RPP30 mRNA

PMID:17942748
decreases expressionISORGD:15951166480464CTDTetrachlorodibenzodioxin results in decreased expression of RPP30 mRNA

PMID:21215274
multiple interactionsISORGD:15951166480464CTDAHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of RPP30 mRNA]

PMID:21215274
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.