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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1321631
Species: Homo sapiens
RGD Object: Gene
Symbol: SORCS2
Name: sortilin related VPS10 domain containing receptor 2
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SORCS2affects expressionISOSorcs2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of SORCS2 mRNAPMID:26377647
SORCS2increases expressionISOSorcs2 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of SORCS2 mRNAPMID:34747641
SORCS2increases expressionISOSorcs2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of SORCS2 mRNAPMID:19933214
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