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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1320779
Species: Mus musculus
RGD Object: Gene
Symbol: Sema3b
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sema3baffects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of SEMA3B mRNAPMID:21570461
Sema3bdecreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of SEMA3B mRNAPMID:33956508
Sema3bmultiple interactionsEXP 6480464CTDTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to SEMA3B promoter]PMID:19654925
Sema3baffects expressionISOSema3b (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of SEMA3B mRNAPMID:22298810
Sema3bdecreases expressionISOSEMA3B (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of SEMA3B mRNAPMID:19619570
Sema3bincreases expressionISOSema3b (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of SEMA3B mRNAPMID:32109520 PMID:33387578
Sema3bmultiple interactionsISOSEMA3B (Homo sapiens)6480464CTD[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of SEMA3B mRNAPMID:19619570
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