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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1318995
Species: Homo sapiens
RGD Object: Gene
Symbol: MMP15
Name: matrix metallopeptidase 15
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MMP15affects expressionISOMmp15 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of MMP15 mRNAPMID:22298810
MMP15decreases expressionISOMmp15 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of MMP15 mRNAPMID:21215274 PMID:32109520
MMP15decreases expressionISOMmp15 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of MMP15 mRNAPMID:19770486 PMID:25975270 PMID:26290441
MMP15increases expressionISOMmp15 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of MMP15 mRNAPMID:33387578 PMID:34747641
MMP15increases expressionISOMmp15 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of MMP15 mRNAPMID:29673856
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