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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1318503
Species: Homo sapiens
RGD Object: Gene
Symbol: PDZD8
Name: PDZ domain containing 8
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PDZD8affects expressionISOPdzd8 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of PDZD8 mRNAPMID:21570461
PDZD8decreases expressionISOPdzd8 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of PDZD8 mRNAPMID:33387578
PDZD8decreases expressionISOPdzd8 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of PDZD8 mRNAPMID:19770486
PDZD8increases expressionISOPdzd8 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of PDZD8 mRNAPMID:19465110 PMID:21354282
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