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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1316207
Species: Homo sapiens
RGD Object: Gene
Symbol: ABCA3
Name: ATP binding cassette subfamily A member 3
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ABCA3affects expressionISOAbca3 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of ABCA3 mRNAPMID:21570461
ABCA3increases expressionISOAbca3 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of ABCA3 mRNAPMID:21215274
ABCA3multiple interactionsISOAbca3 (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of ABCA3 mRNAPMID:28433925
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