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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1314683
Species: Homo sapiens
RGD Object: Gene
Symbol: IGFBP7
Name: insulin like growth factor binding protein 7
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IGFBP7decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of IGFBP7 mRNAPMID:17101203 PMID:20106945 PMID:21632981
IGFBP7affects expressionISOIgfbp7 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of IGFBP7 mRNAPMID:34747641
IGFBP7decreases expressionISOIgfbp7 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of IGFBP7 mRNAPMID:15034205 PMID:33956508
IGFBP7multiple interactionsISOIgfbp7 (Mus musculus)6480464CTDAHR protein promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of IGFBP7 mRNA]PMID:15034205
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