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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1314311
Species: Mus musculus
RGD Object: Gene
Symbol: Cux2
Name: cut-like homeobox 2
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cux2affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of CUX2 mRNAPMID:28922406
Cux2decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of CUX2 mRNAPMID:26290441
Cux2increases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of CUX2 mRNAPMID:21889950 PMID:24058054
Cux2multiple interactionsEXP 6480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CUX2 mRNA; Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CUX2 promoter]PMID:17942748 PMID:19654925
Cux2affects expressionISOCUX2 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin affects the expression of CUX2 mRNAPMID:22298810
Cux2decreases expressionISOCux2 (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of CUX2 mRNAPMID:21215274
Cux2decreases expressionISOCUX2 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of CUX2 mRNAPMID:19692669 PMID:20106945
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