GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccng2 | affects expression | EXP | | 6480464 | CTD | Tetrachlorodibenzodioxin affects the expression of CCNG2 mRNA | PMID:21570461 | Ccng2 | multiple interactions | EXP | | 6480464 | CTD | [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of CCNG2 mRNA | PMID:25975270 | Ccng2 | affects expression | ISO | Ccng2 (Rattus norvegicus) | 6480464 | CTD | Tetrachlorodibenzodioxin affects the expression of CCNG2 mRNA | PMID:22298810 | Ccng2 | increases expression | ISO | Ccng2 (Rattus norvegicus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of CCNG2 mRNA | PMID:34747641 | Ccng2 | increases expression | ISO | CCNG2 (Homo sapiens) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of CCNG2 mRNA; Tetrachlorodibenzodioxin results in increased expression of CCNG2 protein | PMID:19574409 PMID:19619570 PMID:20348232 PMID:22596188 | Ccng2 | multiple interactions | ISO | CCNG2 (Homo sapiens) | 6480464 | CTD | 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CCNG2 mRNA]; [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of CCNG2 mRNA; AHR protein promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [ESR1 protein binds to CCNG2 gene]]; ESR1 protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CCNG2 mRNA]; FOXA1 protein affects the reaction [Tetrachlorodibenzodioxin inhibits the reaction [[Estradiol binds to ESR1 protein] which results in decreased expression of CCNG2 mRNA]]; FOXA1 protein affects the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CCNG2 promoter]]; FOXA1 protein affects the reaction [Tetrachlorodibenzodioxin promotes the reaction [NCOA3 protein binds to CCNG2 promoter]]; FOXA1 protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CCNG2 mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [[Estradiol binds to ESR1 protein] which results in decreased expression of CCNG2 mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [Estradiol inhibits the reaction [NCOA3 protein binds to CCNG2 promoter]]; Tetrachlorodibenzodioxin promotes the reaction [[[AHR protein binds to FOXA1 protein] which binds to CCNG2 promoter] which results in increased expression of CCNG2 mRNA]; Tetrachlorodibenzodioxin promotes the reaction [[[AHR protein binds to NCOA3 protein binds to FOXA1 protein] which binds to CCNG2 promoter] which results in increased expression of CCNG2 mRNA]; Tetrachlorodibenzodioxin promotes the reaction [[[AHR protein binds to NCOA3 protein binds to FOXA1 protein] which binds to CCNG2 promoter] which results in increased expression of CCNG2 protein]; Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CCNG2 gene]; Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CCNG2 promoter]; Tetrachlorodibenzodioxin promotes the reaction [ESR1 protein binds to CCNG2 gene]; Tetrachlorodibenzodioxin promotes the reaction [FOXA1 protein binds to CCNG2 enhancer]; Tetrachlorodibenzodioxin promotes the reaction [FOXA1 protein binds to CCNG2 promoter]; Tetrachlorodibenzodioxin promotes the reaction [NCOA3 protein binds to CCNG2 promoter] | PMID:19574409 PMID:19619570 PMID:22596188 | | ||||||||||||||||||||||
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