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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1312065
Species: Homo sapiens
RGD Object: Gene
Symbol: DSTN
Name: destrin, actin depolymerizing factor
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
DSTNincreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of DSTN mRNAPMID:20106945 PMID:21632981
DSTNaffects expressionISODstn (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of DSTN mRNAPMID:21570461
DSTNincreases expressionISODstn (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in increased expression of DSTN mRNAPMID:34747641
DSTNmultiple interactionsISODstn (Mus musculus)6480464CTD[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of DSTN mRNA; [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DSTN mRNAPMID:16214954 PMID:17942748
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