GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Srxn1 | decreases expression | EXP | | 6480464 | CTD | Tetrachlorodibenzodioxin results in decreased expression of SRXN1 mRNA | PMID:32109520 | Srxn1 | increases expression | EXP | | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of SRXN1 mRNA | PMID:18796159 PMID:27136898 | Srxn1 | affects expression | ISO | Srxn1 (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin affects the expression of SRXN1 mRNA | PMID:20702594 PMID:21570461 PMID:26377647 | Srxn1 | increases expression | ISO | SRXN1 (Homo sapiens) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of SRXN1 mRNA | PMID:20106945 PMID:21632981 PMID:26198647 PMID:26238291 | Srxn1 | increases expression | ISO | Srxn1 (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of SRXN1 mRNA | PMID:18796159 PMID:21851831 PMID:25975270 PMID:26290441 | Srxn1 | multiple interactions | ISO | SRXN1 (Homo sapiens) | 6480464 | CTD | [Endosulfan co-treated with Tetrachlorodibenzodioxin] results in increased expression of SRXN1 mRNA | PMID:26159488 | Srxn1 | multiple interactions | ISO | Srxn1 (Mus musculus) | 6480464 | CTD | 2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of SRXN1 mRNA]; [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of SRXN1 mRNA; [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SRXN1 mRNA; [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of SRXN1 mRNA; Tetrachlorodibenzodioxin promotes the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of SRXN1 mRNA] | PMID:16214954 PMID:17942748 PMID:21851831 PMID:25975270 | |
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