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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307250
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hoxc10
Name: homeo box C10
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hoxc10decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of HOXC10 mRNAPMID:33387578
Hoxc10affects expressionISOHoxc10 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of HOXC10 mRNAPMID:24058054
Hoxc10multiple interactionsISOHOXC10 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to HOXC10 gene]PMID:19574409
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