GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Lpin2 | decreases expression | EXP | | 6480464 | CTD | Tetrachlorodibenzodioxin results in decreased expression of LPIN2 mRNA | PMID:21215274 PMID:33387578 | Lpin2 | affects expression | ISO | Lpin2 (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin affects the expression of LPIN2 mRNA | PMID:21570461 | Lpin2 | increases expression | ISO | Lpin2 (Mus musculus) | 6480464 | CTD | Tetrachlorodibenzodioxin results in increased expression of LPIN2 mRNA | PMID:15328365 PMID:15800033 PMID:16611356 PMID:19770486 PMID:21889950 PMID:23864506 PMID:23994337 PMID:25975270 PMID:26290441 PMID:28213091 PMID:28238261 | Lpin2 | multiple interactions | ISO | Lpin2 (Mus musculus) | 6480464 | CTD | [Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of LPIN2 mRNA; [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of LPIN2 mRNA; Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to LPIN2 gene] | PMID:25975270 PMID:28213091 PMID:28433925 | |
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