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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1303089
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gsn
Name: gelsolin
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of GSN mRNA

PMID:22298810
decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of GSN mRNA

PMID:21215274
affects expressionISORGD:15506606480464CTDTetrachlorodibenzodioxin affects the expression of GSN mRNA

PMID:26377647
decreases expressionISORGD:15506606480464CTDTetrachlorodibenzodioxin results in decreased expression of GSN mRNA

PMID:20044593
increases expressionISORGD:13463756480464CTDTetrachlorodibenzodioxin results in increased expression of GSN mRNA

PMID:20044593, PMID:20106945, PMID:21632981
increases expressionISORGD:15506606480464CTDTetrachlorodibenzodioxin results in increased expression of GSN mRNA

PMID:17035482, PMID:19770486
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.