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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11134
Species: Mus musculus
RGD Object: Gene
Symbol: Ppp3ca
Name: protein phosphatase 3, catalytic subunit, alpha isoform
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppp3caaffects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of PPP3CA mRNAPMID:21570461
Ppp3caaffects expressionISOPpp3ca (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin affects the expression of PPP3CA mRNAPMID:34747641
Ppp3cadecreases expressionISOPpp3ca (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of PPP3CA mRNAPMID:21215274 PMID:32109520 PMID:33387578
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