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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10297
Species: Mus musculus
RGD Object: Gene
Symbol: Cbs
Name: cystathionine beta-synthase
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cbsaffects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of CBS mRNAPMID:21570461
Cbsdecreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of CBS mRNAPMID:19770486 PMID:28213091
Cbsmultiple interactionsEXP 6480464CTD[Tetrachlorodibenzodioxin binds to AHR protein] which results in decreased expression of CBS mRNAPMID:16214954
Cbsdecreases expressionISOCbs (Rattus norvegicus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of CBS mRNAPMID:21215274 PMID:21724226 PMID:32109520
Cbsdecreases expressionISOCBS (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in decreased expression of CBS mRNAPMID:20106945 PMID:21632981
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