GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cxcl10 | multiple interactions | EXP | | 6480464 | CTD | [Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL10 mRNA; [Zinc co-treated with Nickel co-treated with Cobalt] affects the reaction [Dietary Fats affects the expression of CXCL10 mRNA]; TNF protein inhibits the reaction [[Zinc co-treated with Nickel co-treated with Cobalt co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CXCL10 mRNA] | PMID:23503329 | Cxcl10 | increases expression | ISO | CXCL10 (Homo sapiens) | 6480464 | CTD | Nickel results in increased expression of CXCL10 mRNA | PMID:24768652 PMID:25583101 | Cxcl10 | increases expression | ISO | Cxcl10 (Rattus norvegicus) | 6480464 | CTD | Nickel analog results in increased expression of CXCL10 mRNA; Nickel analog results in increased expression of CXCL10 protein | PMID:22700867 | Cxcl10 | multiple interactions | ISO | Cxcl10 (Rattus norvegicus) | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of CXCL10 mRNA]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of CXCL10 protein]]; PDGFB protein promotes the reaction [Nickel analog results in increased expression of CXCL10 mRNA]; PDGFB protein promotes the reaction [Nickel analog results in increased expression of CXCL10 protein] | PMID:22700867 | |
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