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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1317808
Species: Homo sapiens
RGD Object: Gene
Symbol: H3-4
Name: H3.4 histone, cluster member
Acc ID: CHEBI:28112
Term: nickel atom
Definition: Chemical element (nickel group element atom) with atomic number 28.
Chemical ID: MESH:D009532
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
H3-4increases methylationEXP 6480464CTDNickel results in increased methylation of H3-4 proteinPMID:16648469 PMID:21385672
H3-4multiple interactionsEXP 6480464CTD[Arsenic co-treated with Nickel] results in increased acetylation of H3-4 protein; [Arsenic co-treated with Nickel] results in increased methylation of H3-4 proteinPMID:21385672
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