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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307303
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ndrg1
Name: N-myc downstream regulated 1
Acc ID: CHEBI:28112
Term: nickel atom
Definition: Chemical element (nickel group element atom) with atomic number 28.
Chemical ID: MESH:D009532
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ndrg1increases expressionISONDRG1 (Homo sapiens)6480464CTDNickel results in increased expression of NDRG1 mRNA; Nickel results in increased expression of NDRG1 proteinPMID:15341671 PMID:16386771
Ndrg1increases expressionISONdrg1 (Mus musculus)6480464CTDNickel results in increased expression of NDRG1 mRNAPMID:18922574
Ndrg1multiple interactionsISONDRG1 (Homo sapiens)6480464CTDHIF1A protein promotes the reaction [Nickel results in increased expression of NDRG1 mRNA]; HIF1A protein promotes the reaction [Nickel results in increased expression of NDRG1 protein]PMID:15341671
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