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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735361
Species: Homo sapiens
RGD Object: Gene
Symbol: NR2F2
Name: nuclear receptor subfamily 2 group F member 2
Acc ID: CHEBI:28088
Term: genistein
Definition: A 7-hydroxyisoflavone with additional hydroxy groups at positions 5 and 4'. It is a phytoestrogenic isoflavone with antioxidant properties.
Chemical ID: MESH:D019833
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NR2F2decreases expressionISONr2f2 (Rattus norvegicus)6480464CTDGenistein results in decreased expression of NR2F2 mRNAPMID:22504913
NR2F2decreases expressionISONr2f2 (Mus musculus)6480464CTDGenistein results in decreased expression of NR2F2 mRNAPMID:27181934
NR2F2multiple interactionsISONr2f2 (Mus musculus)6480464CTD[Genistein co-treated with mono-(2-ethylhexyl)phthalate] affects the expression of NR2F2 mRNAPMID:27181934
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