GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | LEP | decreases response to substance | EXP | | 6480464 | CTD | Genistein results in decreased susceptibility to LEP protein | PMID:11342529 | LEP | multiple interactions | EXP | | 6480464 | CTD | Genistein inhibits the reaction [LEP protein results in increased chemical synthesis of Reactive Oxygen Species]; Genistein inhibits the reaction [LEP protein results in increased expression of CCL2] | PMID:11342529 | LEP | decreases expression | ISO | Lep (Mus musculus) | 6480464 | CTD | Genistein results in decreased expression of LEP mRNA; Genistein results in decreased expression of LEP protein | PMID:18359623 | |
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