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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3073
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc3a2
Name: solute carrier family 3 member 2
Acc ID: CHEBI:28088
Term: genistein
Definition: 7-Hydroxyisoflavone with additional hydroxy groups at positions 5 and 4'. It is a phytoestrogenic isoflavone with antioxidant properties.
Chemical ID: MESH:D019833
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:7357166480464CTDGenistein results in increased expression of SLC3A2 mRNA, Genistein results in increased expression of SLC3A2 protein

PMID:19371625, PMID:20884965, PMID:23019147
multiple interactionsISORGD:7357166480464CTDESR1 promotes the reaction [Genistein results in increased expression of SLC3A2 protein]

PMID:20884965
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.