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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2855
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ibsp
Name: integrin-binding sialoprotein
Acc ID: CHEBI:28088
Term: genistein
Definition: A 7-hydroxyisoflavone with additional hydroxy groups at positions 5 and 4'. It is a phytoestrogenic isoflavone with antioxidant properties.
Chemical ID: MESH:D019833
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ibspmultiple interactionsISOIBSP (Homo sapiens)6480464CTD[Genistein co-treated with ESR1] results in increased expression of BSP mRNA; [Genistein co-treated with ESR2] results in increased expression of BSP mRNAPMID:19347870
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