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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1349475
Species: Homo sapiens
RGD Object: Gene
Symbol: HSPA1A
Name: heat shock protein family A (Hsp70) member 1A
Acc ID: CHEBI:28088
Term: genistein
Definition: A 7-hydroxyisoflavone with additional hydroxy groups at positions 5 and 4'. It is a phytoestrogenic isoflavone with antioxidant properties.
Chemical ID: MESH:D019833
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HSPA1Adecreases expressionEXP 6480464CTDGenistein results in decreased expression of HSPA1A mRNAPMID:26865667
HSPA1Adecreases expressionISOHspa1a (Mus musculus)6480464CTDGenistein results in decreased expression of HSPA1A mRNAPMID:24967385
HSPA1Aincreases expressionISOHspa1a (Rattus norvegicus)6480464CTDGenistein results in increased expression of HSPA1A mRNAPMID:17010207
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