Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Pathways

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2916
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ins2
Name: insulin 2
Acc ID: CHEBI:28087
Term: glycogen
Definition: A polydisperse, highly branched glucan composed of chains of D-glucopyranose residues in α(1→4) glycosidic linkage, joined together by α(1→6) glycosidic linkages. A small number of α(1→3) glycosidic linkages and some cumulative α(1→6) links also may occur. The branches in glycogen typically contain 8 to 12 glucose residues.
Chemical ID: MESH:D006003
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ins2increases abundanceISOINS (Homo sapiens)6480464CTDINS protein results in increased abundance of GlycogenPMID:31228551
Ins2increases chemical synthesisISOINS (Homo sapiens)6480464CTDINS protein results in increased chemical synthesis of GlycogenPMID:15864539 PMID:21632903
Ins2multiple interactionsISOINS (Homo sapiens)6480464CTDEstradiol promotes the reaction [INS protein results in increased chemical synthesis of Glycogen]; Glucose inhibits the reaction [INS protein results in increased chemical synthesis of Glycogen]; mono-(2-ethylhexyl)phthalate inhibits the reaction [INS protein results in increased abundance of Glycogen]; RBP4 protein promotes the reaction [mono-(2-ethylhexyl)phthalate inhibits the reaction [INS protein results in increased abundance of Glycogen]]; Testosterone promotes the reaction [INS protein results in increased chemical synthesis of Glycogen]PMID:15864539 PMID:21632903 PMID:31228551
Go Back to source page   Continue to Ontology report