Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2916
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ins2
Name: insulin 2
Acc ID: CHEBI:28087
Term: glycogen
Definition: A polydisperse, highly branched glucan composed of chains of D-glucopyranose residues in alpha(1->4) glycosidic linkage, joined together by alpha(1->6) glycosidic linkages. A small number of alpha(1->3) glycosidic linkages and some cumulative alpha(1->6) links also may occur. The branches in glycogen typically contain 8 to 12 glucose residues.
Chemical ID: MESH:D006003
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ins2increases abundanceISORGD:7310566480464CTDINS protein results in increased abundance of Glycogen

PMID:31228551
Ins2increases chemical synthesisISORGD:7310566480464CTDINS protein results in increased chemical synthesis of Glycogen

PMID:15864539, PMID:21632903
Ins2multiple interactionsISORGD:7310566480464CTDEstradiol promotes the reaction [INS protein results in increased chemical synthesis of Glycogen], Glucose inhibits the reaction [INS protein results in increased chemical synthesis of Glycogen], mono-(2-ethylhexyl)phthalate inhibits the reaction [INS protein results in increased abundance of Glycogen], RBP4 protein promotes the reaction [mono-(2-ethylhexyl)phthalate inhibits the reaction [INS protein results in increased abundance of Glycogen]], Testosterone promotes the reaction [INS protein results in increased chemical synthesis of Glycogen]

PMID:15864539, PMID:21632903, PMID:31228551
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.