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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2670
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gck
Name: glucokinase
Acc ID: CHEBI:28077
Term: rifampicin
Definition: A member of the class of rifamycins that is a a semisynthetic antibiotic derived from Amycolatopsis rifamycinica (previously known as Amycolatopsis mediterranei and Streptomyces mediterranei).
Chemical ID: MESH:D012293
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gckdecreases expressionISOGCK (Homo sapiens)6480464CTDRifampin results in decreased expression of GCK proteinPMID:26616219
Gckmultiple interactionsISOGCK (Homo sapiens)6480464CTDNR1I2 protein promotes the reaction [Rifampin results in decreased expression of GCK protein]PMID:26616219
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