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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352024
Species: Homo sapiens
RGD Object: Gene
Symbol: CXCL10
Name: C-X-C motif chemokine ligand 10
Acc ID: CHEBI:28077
Term: rifampicin
Definition: A member of the class of rifamycins that is a a semisynthetic antibiotic derived from Amycolatopsis rifamycinica (previously known as Amycolatopsis mediterranei and Streptomyces mediterranei).
Chemical ID: MESH:D012293
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CXCL10affects expressionISOCxcl10 (Rattus norvegicus)6480464CTDRifampin affects the expression of CXCL10 proteinPMID:25051504
CXCL10multiple interactionsISOCxcl10 (Mus musculus)6480464CTD[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CXCL10 mRNAPMID:21224054
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