GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | SLCO1B1 | affects uptake | EXP | | 6480464 | CTD | SLCO1B1 protein affects the uptake of Rifampin | PMID:15652233 | SLCO1B1 | decreases activity | EXP | | 6480464 | CTD | Rifampin results in decreased activity of SLCO1B1 protein | PMID:23564645 PMID:31830554 PMID:32259555 PMID:32305507 | SLCO1B1 | increases expression | EXP | | 6480464 | CTD | Rifampin results in increased expression of SLCO1B1 mRNA | PMID:15670600 PMID:16837569 | SLCO1B1 | multiple interactions | EXP | | 6480464 | CTD | [Rifampin results in decreased activity of SLCO1B1 protein] which results in decreased uptake of Fluvastatin; Rifampin inhibits the reaction [SLCO1B1 protein results in increased import of estradiol-17 beta-glucuronide]; Rifampin inhibits the reaction [SLCO1B1 protein results in increased import of Taurocholic Acid]; Rifampin inhibits the reaction [SLCO1B1 protein results in increased uptake of and results in increased susceptibility to cerivastatin]; Rifampin inhibits the reaction [SLCO1B1 protein results in increased uptake of and results in increased susceptibility to cyanoginosin LR]; Rifampin inhibits the reaction [SLCO1B1 protein results in increased uptake of and results in increased susceptibility to Fluvastatin]; Rifampin inhibits the reaction [SLCO1B1 protein results in increased uptake of and results in increased susceptibility to pitavastatin]; Rifampin inhibits the reaction [SLCO1B1 protein results in increased uptake of and results in increased susceptibility to Pravastatin]; Rifampin inhibits the reaction [SLCO1B1 protein results in increased uptake of and results in increased susceptibility to Rosuvastatin Calcium]; Rifampin inhibits the reaction [SLCO1B1 protein results in increased uptake of epyrifenacil metabolite]; Rifampin inhibits the reaction [SLCO1B1 protein results in increased uptake of estradiol-17 beta-glucuronide]; Rifampin inhibits the reaction [SLCO1B1 protein results in increased uptake of estrone sulfate]; Rifampin inhibits the reaction [SLCO1B1 protein results in increased uptake of Mesalamine]; Rifampin inhibits the reaction [SLCO1B1 protein results in increased uptake of Sulfobromophthalein]; Rifampin inhibits the reaction [SLCO1B1 protein results in increased uptake of Ursodeoxycholic Acid metabolite] | PMID:16479312 PMID:21430235 PMID:23564645 PMID:26750564 PMID:31299240 PMID:32003934 PMID:32259555 PMID:32305507 PMID:34619012 | | ||||||||||||||||||||||
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