GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp1a1 | multiple interactions | ISO | Cyp1a1 (Mus musculus) | 6480464 | CTD | [Azacitidine co-treated with Butyrates] inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene promotes the reaction [AHR protein binds to CYP1A1 promoter]]]; [Azacitidine co-treated with Butyrates] inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]]; Azacitidine inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene promotes the reaction [AHR protein binds to CYP1A1 promoter]]]; Azacitidine inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]]; Butyrates inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene promotes the reaction [AHR protein binds to CYP1A1 promoter]]]; Butyrates inhibits the reaction [Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]]; Chromium inhibits the reaction [Benzo(a)pyrene inhibits the reaction [HDAC1 protein binds to CYP1A1 promoter]]; Chromium inhibits the reaction [Benzo(a)pyrene promotes the reaction [H3F4 protein modified form binds to CYP1A1 promoter]]; Chromium inhibits the reaction [Benzo(a)pyrene promotes the reaction [H4C16 protein modified form binds to CYP1A1 promoter]]; Chromium inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A1 protein]; Chromium inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; Chromium inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Chromium inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Chromium inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Chromium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Chromium promotes the reaction [[DNMT1 protein binds to HDAC1 protein] which binds to CYP1A1 promoter]; Chromium promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; Chromium promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 protein]; Chromium promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Chromium promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]; Chromium promotes the reaction [HDAC1 protein binds to CYP1A1 promoter]; Chromium promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Chromium promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Chromium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Chromium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]; HDAC1 protein affects the reaction [Chromium results in decreased expression of CYP1A1 mRNA] | PMID:10972992 PMID:14625279 PMID:15337587 PMID:17682057 | | ||||||||||||||||||||||
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