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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:28073
Term: chromium atom
Definition: A chromium group element atom that has atomic number 24.
Chemical ID: MESH:D002857
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxincreases cleavageISOBAX (Homo sapiens)6480464CTDChromium results in increased cleavage of BAX proteinPMID:31953414
Baxincreases expressionISOBAX (Homo sapiens)6480464CTDChromium results in increased expression of BAX mRNAPMID:18602874
Baxmultiple interactionsISOBAX (Homo sapiens)6480464CTD[Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased expression of BAX protein; Luteolin affects the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased expression of BAX protein]PMID:29115570
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