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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62396
Species: Mus musculus
RGD Object: Gene
Symbol: Ddit3
Name: DNA-damage inducible transcript 3
Acc ID: CHEBI:28061
Term: alpha-D-galactose
Definition: D-Galactopyranose having alpha-configuration at the anomeric centre.
Chemical ID: MESH:D005690
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:691656480464CTDGalactose results in increased expression of DDIT3 protein

PMID:23036742
multiple interactionsISORGD:691656480464CTD[Galactose co-treated with Glucose deficiency] promotes the reaction [leflunomide results in increased expression of DDIT3 protein], Phycocyanin inhibits the reaction [Galactose results in increased expression of DDIT3 protein]

PMID:23036742, PMID:29427785
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.