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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:28061
Term: alpha-D-galactose
Definition: D-Galactopyranose having alpha-configuration at the anomeric centre.
Chemical ID: MESH:D005690
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxincreases expressionEXP 6480464CTDGalactose results in increased expression of BAX mRNA; Galactose results in increased expression of BAX proteinPMID:25892055 PMID:34673010 PMID:35259467
Baxmultiple interactionsEXP 6480464CTDagomelatine inhibits the reaction [Galactose results in increased expression of BAX protein]; Galactose promotes the reaction [sodium arsenite results in increased expression of BAX mRNA]; Melatonin inhibits the reaction [Galactose results in increased expression of BAX protein]; Saponins inhibits the reaction [Galactose results in increased expression of BAX protein]PMID:25892055 PMID:34673010 PMID:35259467
Baxincreases expressionISOBAX (Homo sapiens)6480464CTDGalactose results in increased expression of BAX proteinPMID:23036742
Baxmultiple interactionsISOBAX (Homo sapiens)6480464CTDPhycocyanin inhibits the reaction [Galactose results in increased expression of BAX protein]PMID:23036742
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