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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11476
Species: Mus musculus
RGD Object: Gene
Symbol: Ugt1a1
Name: UDP glucuronosyltransferase 1 family, polypeptide A1
Acc ID: CHEBI:27974
Term: estriol
Definition: A 3-hydroxy steroid that is estra-1,3,5(10)-trien-3-ol substituted by additional hydroxy groups at positions 16 and 17 (16alpha,17beta-stereoisomer).
Chemical ID: MESH:D004964
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases glucuronidationISORGD:13500186480464CTDUGT1A1 protein results in increased glucuronidation of Estriol, UGT1A1 protein results in increased glucuronidation of Estriol analog

PMID:15117964
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.