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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737196
Species: Mus musculus
RGD Object: Gene
Symbol: Junb
Name: jun B proto-oncogene
Acc ID: CHEBI:27958
Term: cocaine
Definition: A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca.
Chemical ID: MESH:D003042
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Junbincreases expressionEXP 6480464CTDCocaine results in increased expression of JUNB proteinPMID:16263220 PMID:18355967
Junbmultiple interactionsEXP 6480464CTDSL 327 inhibits the reaction [Cocaine results in increased expression of JUNB protein]PMID:16263220
Junbaffects expressionISOJunb (Rattus norvegicus)6480464CTDCocaine affects the expression of JUNB mRNAPMID:20187946
Junbaffects expressionISOJUNB (Homo sapiens)6480464CTDCocaine affects the expression of JUNB proteinPMID:15814102
Junbincreases expressionISOJunb (Rattus norvegicus)6480464CTDCocaine results in increased expression of JUNB mRNAPMID:11860464 PMID:1347779
Junbmultiple interactionsISOJunb (Rattus norvegicus)6480464CTDCocaine promotes the reaction [[SK&F 81297 co-treated with Quinpirole] results in increased expression of JUNB protein]; NPPC protein inhibits the reaction [Cocaine results in increased expression of JUNB mRNA]PMID:11860464 PMID:12122080
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