GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CAMK2A | affects response to substance | ISO | Camk2a (Mus musculus) | 6480464 | CTD | CAMK2A affects the susceptibility to Cocaine | PMID:14725635 | CAMK2A | increases expression | ISO | Camk2a (Rattus norvegicus) | 6480464 | CTD | Cocaine results in increased expression of CAMK2A protein | PMID:14725635 | CAMK2A | multiple interactions | ISO | Camk2a (Mus musculus) | 6480464 | CTD | Cocaine results in increased expression of and results in increased phosphorylation of CAMK2A protein; Nifedipine inhibits the reaction [Cocaine results in increased expression of and results in increased phosphorylation of CAMK2A protein] | PMID:28194001 | CAMK2A | multiple interactions | ISO | Camk2a (Rattus norvegicus) | 6480464 | CTD | 7-chlorokynurenic acid inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of CAMK2A protein]; Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]; Cocaine results in increased phosphorylation of and results in increased activity of CAMK2A protein; KN 93 inhibits the reaction [Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]]; Sodium Benzoate promotes the reaction [Cocaine results in increased phosphorylation of and results in increased activity of CAMK2A protein] | PMID:17609678 PMID:19217379 | |
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