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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735493
Species: Homo sapiens
RGD Object: Gene
Symbol: GPR88
Name: G protein-coupled receptor 88
Acc ID: CHEBI:27958
Term: cocaine
Definition: A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca.
Chemical ID: MESH:D003042
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GPR88affects expressionISOGpr88 (Rattus norvegicus)6480464CTDCocaine affects the expression of GPR88 mRNAPMID:20187946
GPR88increases expressionISOGpr88 (Mus musculus)6480464CTDCocaine deficiency results in increased expression of GPR88 mRNAPMID:27126842
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