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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735406
Species: Mus musculus
RGD Object: Gene
Symbol: Camk4
Name: calcium/calmodulin-dependent protein kinase IV
Acc ID: CHEBI:27958
Term: cocaine
Definition: A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca.
Chemical ID: MESH:D003042
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Camk4decreases response to substanceEXP 6480464CTDCAMK4 protein results in decreased susceptibility to CocainePMID:19001277
Camk4increases response to substanceISOCAMK4 (Homo sapiens)6480464CTDCAMK4 promoter SNP results in increased susceptibility to CocainePMID:19001277
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