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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732451
Species: Homo sapiens
RGD Object: Gene
Symbol: RPS6KA1
Name: ribosomal protein S6 kinase A1
Acc ID: CHEBI:27958
Term: cocaine
Definition: A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca.
Chemical ID: MESH:D003042
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
RPS6KA1multiple interactionsISORps6ka1 (Rattus norvegicus)6480464CTDCocaine promotes the reaction [RPS6KA1 protein binds to CREB1 protein]; Cocaine results in increased phosphorylation of and results in increased activity of RPS6KA1 proteinPMID:15470197
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