GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | HTR1B | affects activity | ISO | Htr1b (Rattus norvegicus) | 6480464 | CTD | Cocaine affects the activity of HTR1B protein | PMID:17074068 | HTR1B | increases response to substance | ISO | Htr1b (Mus musculus) | 6480464 | CTD | HTR1B mutant form results in increased susceptibility to Cocaine | PMID:9603521 | HTR1B | multiple interactions | ISO | Htr1b (Rattus norvegicus) | 6480464 | CTD | [3-(1,2,5,6-tetrahydropyrid-4-yl)pyrrolo(3,2-b)pyrid-5-one binds to and results in increased activity of HTR1B protein] which affects the susceptibility to Cocaine; [5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1H indole binds to and results in increased activity of HTR1B protein] which affects the susceptibility to Cocaine; [CP 94253 binds to and results in increased activity of HTR1B protein] which affects the susceptibility to Cocaine | PMID:9822762 | | ||||||||||||||||||||||
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